If you’re looking for a probiotic but don’t know where to start, you’ve come to the right place. Read on to find out more about probiotics, how they might benefit you, and discover our top picks for the best probiotics in 2023. 

Potential Benefits of Taking Probiotics*

Adding a probiotic to your routine may help support:

  • Digestion*
  • Overall Gut Health* 
  • Occasional Bloat*
  • Immune Health*
  • Occasional Constipation and Excess Gas*

What Is A Probiotic?

Probiotics are live bacteria and yeast that live in your gut microbiome.

Whenever you see the term “gut microbiome,” it’s referring to all of the microorganisms living within your gut. Some of them may be potentially harmful, so-called “bad” bacteria. On the other hand, some are thought to be beneficial, often called “good” or “friendly” bacteria, aka probiotics. [1, 2, 3, 4] 

Researchers believe that having optimal gut health typically means having a good balance between the “bad” bacteria and the “good" bacteria. Ideally, they should co-exist peacefully within the gut.[1, 2, 3, 4] 

Probiotics can be found in some fermented foods like yogurt, kefir, kimchi, sauerkraut, and miso. They are also available as dietary supplements. This may be more convenient for some people to consume, especially if they struggle to eat enough probiotic-rich foods.  

Note: Individual results may vary. The benefits stated are based on personal experiences and subjective feedback and may vary from person to person.


The Best Probiotics of 2023 

Latest update: 

  • Comfortable Regularity* 
  • Healthy Weight Management*
  • Energy*
  • Healthy skin*

DISCLAIMER: This scientific research is for informational purposes only. The results reported may not necessarily occur in all individuals. Primal Harvest provides this information as a service but does not endorse it. This information should not be read to recommend or endorse any specific products.

1. Integrative HMP (iHMP) Research Network Consortium. “The Integrative Human Microbiome Project: dynamic analysis of microbiome-host omics profiles….” Cell host & microbe vol. 16,3 (2014): 276-89. doi:10.1016/j.chom.2014.08.014

2. Sender, Ron et al. “Revised Estimates for the Number of Human and Bacteria Cells in the Body.” PLoS biology vol. 14,8 e1002533. 19 Aug. 2016, doi:10.1371/journal.pbio.1002533

3. Durack, Juliana, and Susan V Lynch. “The gut microbiome…” The Journal of experimental medicine vol. 216,1 (2019): 20-40. doi:10.1084/jem.20180448

4. Al Bander, Zahraa et al. “The Gut Microbiota…: An Overview.” International journal of environmental research and public health vol. 17,20 7618. 19 Oct. 2020, doi:10.3390/ijerph17207618

To see a list of our other references, please click here



Latest update: 

1. Primal Probiotics

by Primal Harvest[1]



  • Only available online
  • Sometimes runs out of stock




  • Contains 12 dynamic probiotic strains 
  • With 31 billion CFUs
  • Contains PreforPro® prebiotics 
  • Made in the USA with globally sourced ingredients
  • Produced in a GMP-certified facility
  • 90-day money-back guarantee
  • Third-party lab tested
  • Only one capsule a day

Primal Probiotics are formulated with 31 billion CUFs from 12 dynamic probiotic strains, including L. acidophilus, L. rhamnosus, L. casei, B. longum, B. bifidum, and Bacillus coagulans. It combines these with PreforPro® and FOS (Fructo-Oligosaccaride) prebiotics.

Our team liked that the product comes in easy-to-swallow, once-daily capsules, making them convenient to add to a supplement routine.

The formula is third-party lab-tested and made in the USA in a GMP-certified facility. To top it off, they’re backed by a 90-day money-back guarantee. Primal Probiotics’ pricing stands out, especially when you buy multiple bottles or sign up for their easy and convenient subscription service. 

2. Ultimate Flora Probiotic

by RenewLife


  • Over 20 billion CFUs 
  • Made in the USA 
  • 12 diverse strains


  • No prebiotics
  • No L. reuteri, B. longum, or B. bifidum


This product is a great budget probiotic featuring a high CFU count from 12 diverse probiotic strains. It contains both Lacto and Bifido probiotic strains and is delivered in a once daily capsule. Unfortunately, you may note that it was missing some of the probiotic strains we were looking for as well as prebiotics. Although it had a 60-day money-back guarantee but still preferred products with a 90-day guarantee like our number one pick.



3. Probiotics 

by Nature's Bounty


  • Contains L. acidophilus
  • GMP certified 
  • 1 tablet serving size


  • Only 1 probiotic strain
  • No Bifido strains


Nature’s Bounty probiotics is a low-cost, GMP-certified supplement formulated to support digestive health with over 100 million active Lactobacillus acidophilus. This product comes in tablet form, which may be a downside for some since it’s generally thought that probiotics are better formulated in capsule form. However, the main reason this product didn’t make it to the top was that it only contains one probiotic strain.



by Culturelle


  • 1 capsule serving size
  • Includes inulin (chicory root)


  • Only contains 1 probiotic strain
  • Only 12 billion CFUs
  • No Bifido strains 


Digestive Daily Probiotic by Culturelle is a probiotic formula that includes 12 billion CFUs of the probiotic strain Lactobacillus rhamnosus GG. You may note that they include the prebiotic inulin in the formula and that it comes in a one-capsule serving size. However, the fact that this formula only contains one probiotic strain places it fourth on our list.



4. Digestive Daily Probiotic

5. Raw Probiotics

by Garden of Life


  • Once-daily capsule 
  • High CFU count and number of probiotic strains
  • Includes enzymes blend


  • No 90-day money-back guarantee
  • No prebiotics
  • Contains milk


Raw Probiotics by Garden of Life is a once-daily probiotic supplement that includes 100 billion CFUs of both Lacto and Bifido probiotic strains. This product includes a diverse selection of strains and has a high CFU count. While this product was relatively comparable to the other products on this list, the brand does not offer a 90-day money back guarantee which can be disappointing. Additionally, although that the formula includes a digestive blend, you may note that it did not include prebiotics and did contain milk.*



Our Choice

Primal Probiotics

by Primal Harvest[1]

  • USA-made with globally sourced ingredients
  • Potent Probiotic Strains For Men
  • Patented PreforPro® Prebiotics
  • 90-Day Money-Back Guarantee
  • Ultimate Synbiotic Supplement

Learn More

Based on 3732 Reviews of Primal Harvest 

*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. 

Note: The information provided by this website or this company is not a substitute for a face-to-face consultation with your physician and should not be construed as individual medical advice. The testimonials on this website are individual cases and do not guarantee that you will get the same results. All content, including text, graphics, images and information, contained on or available through this web site is for general information purposes only.

Trademarks utilized on our website belong to their respective owners and no implied or expressed endorsement of our website or services is intended. Rankings can be affected by the relationship Smarter Choices has with our top picks.

[1] we have a financial relationship with some of our top picks and partners

© 2023

All Rights Reserved. 

Everyone’s needs are different, but some people who may benefit from taking a probiotic supplement include anyone who:

Who Might Benefit From A Probiotic?*

Note: These statements are not intended to diagnose, treat, cure, or prevent any disease or condition, nor are they intended to be substitutes for professional medical health advice. Always consult your physician or other qualified healthcare provider for accurate advice, diagnosis, and treatment plan.

Wants to maintain regularity*

Finds it hard to consume probiotics through food*

Occasionally experiences digestive issues*

Sometimes has a difficult time passing stool*

Feels bloated or constipated occasionally*

Wants better skin health*

Occasionally feels run-down or sluggish*

Look For:

Try To Avoid:

  • Trying to select the cheapest
  • Not checking the label
  • High serving size
  • Extremely high or low price
  • Inflated CFU numbers
  • Cheap probiotic strains
  • Contains high quality probiotic strains
  • Includes prebiotics
  • 1 capsule serving size
  • Fair price
  • Great customer service and return policy
  • Made in USA
  • Third-party laboratory tested

The Best Probiotics of 2023